Cadherin 13 anticorps (N-Term)

N° du produit ABIN6990560

L’anticorps Lapin Polyclonal anti-Cadherin 13 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter Cadherin 13 dans des échantillons de Humain et Souris.

Aperçu rapide pour Cadherin 13 anticorps (N-Term) (ABIN6990560)

Antigène: Cadherin 13 (CDH13)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Cadherin 13 anticorps

Épitope: AA 150-200, N-Term

Specificité: At least two isoforms of T-cadherin are known to exist.

Purification: T-cadherin Antibody is affinity chromatography purified via peptide column.

Immunogène: T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin. The immunogen is located within amino acids 150 - 200 of T-cadherin.

Isotype: IgG

Information d'application

Indications d'application: T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: T-cadherin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: T-cadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Cadherin 13

Antigène: Cadherin 13 (CDH13)

Autre désignation: T-cadherin

Sujet: T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Poids moléculaire: Predicted: 78, 84 kDa

Observed: 85 kDa

ID gène: 956

NCBI Accession: NP_001248

UniProt: O75355

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization